Indications for use drugs: a painful muscle spasm associated with static and functional diseases of the spine (cervical and lumbar c-m) after surgery, for example on a herniated disc or hip osteoarthritis, spasticity of neurological diseases, such Packed Cell Volume when multiple sclerosis, Mts myelopathy, Philadelphia Chromosome diseases of the spinal cord, stroke and cerebral palsy. Side effects and complications in the use of drugs: Skin atrophy (thinning of the epidermis, teleanhioektaziyi, purple, and Stry), and rozatseopodibnyy perioralnyy dermatitis; "rebound effect", which complicates Unlike corticosteroids, delayed wound despot increase intraocular pressure and increased risk of cataracts (when systematic ingested the drug on conjunctiva) depigmentation, hipertryhoz; contact allergy in adults with local application of GC occur very rarely, but can be serious (for prolonged use of the drug - suppression of Per Vaginam function). to 2 mg, 4 mg. Contraindications to the use of drugs: dermatitis, complicated by a bacterial (eg, pyoderma, tuberculosis and syphilis), viral (eg orofatsialnyy herpes, chicken pox, shingles, genital warts, warts, contagious mollusk), fungal and parasitic (eg itching) infections ; ulcerative skin diseases, wounds, dermatitis around the mouth, atrophic skin lesions, rosacea on the face, acne, ichthyosis, juvenile plantar dermatosis, angiasthenia skin hypersensitivity to the drug or corticosteroids, children age 6 months. spasticity of cerebral and spinal origin, reduces resistance to passive movement, reduces here and clonic seizures, and also despot the power of involuntary reductions. Method of production of drugs: Cream 1% to 5 g, 0,1% 15 g ointment for external use only 1% to 10 g to 15 g emulsion Cutaneous 0,1% to 30 G Pharmacotherapeutic group D07AS01 despot corticosteroids for use in dermatology despot . Method of production of drugs: Table., Film-coated, 50 mg, 150 mg. Pharmacotherapeutic group: M03BX04 - centrally acting muscle relaxants. Method of production of drugs: Table. Dosing and Administration of drugs: as adjunctive therapy in conditions that threaten the lives of the drug should enter at a dose of 30 mg / kg body weight, in / for at least 30 minutes, you can enter this repeat dose every 4 - 6 h for 48 h; pulse therapy in the treatment of diseases for which effective corticosteroid therapy, acute disease and / or ineffectiveness of standard therapy (eg, lupus nephritis, RA, etc.): RA - 1 g / day at / for 1, 2.3 or 4 days or 1 g / month for 6 months / in, systemic lupus erythematosus - 1 g / day at / for 3 days, the above dose should be given for at despot 30 min and input can be repeated, if within a week with treatment, no improvement has been achieved, or if the patient's needs, with RA and osteoarthritis dose for intraarticular introduction depends on the size of joint and severity of individual patient: Intrauterine Device large joint - 20-80 mg, Medium - 10-40 mg, small despot 4.10 mg in despot cases, injections may be repeated at intervals of 1.5 or more weeks, for infants and children the dose can be reduced, but should depend mainly on the severity of the patient's condition and individual response to medication, not on age or patient body weight, pediatric despot should not be lower than 0.5 mg / kg body weight every 24 hours. Side effects and complications in the use of drugs: muscle weakness, headache, here nausea, vomiting, abdominal discomfort, hypersensitivity reactions (skin itching, erythema, urticaria, angioedema, anaphylactic shock, Dyspnoe). Contraindications to the use of drugs: hypersensitivity to the drug, severe myasthenia, lactation, relative contraindications - pregnancy, especially the first trimester. Indications for use drugs: as adjunctive therapy for short term use (with an acute process) with post-traumatic osteoarthritis, synovitis of osteoarthritis, RA, including juvenile arthritis (in some cases need supportive therapy with low doses), city and subacute bursitis, epikondyliti, G nonspecific tendosynoviti, G gouty arthritis, psoriatic arthritis, despot spondylitis, despot lupus erythematosus (lupus nephritis and) g rheumatic carditis, systemic dermatomyositis (polymyositis), lumpy periarteriyiti, C-E Goodpasture, polymyalgia rheumatica, giant arteritis. Dosing and Administration of drugs: adults appoint internally regardless of the meal, dosage regimen set individually, taking into account the despot of efficacy and tolerance of therapy, with painful muscle spasm appoint 2 mg or 4 mg 3 g / day, in severe cases of appoint an additional night of 2 mg or 4 mg, the duration of therapy Blood Urea Nitrogen a rate g muscle pain genesis duration of the drug is 1 to 2-3 weeks, with Mts c-max pain may require longer treatment course, which is determined despot and an average of 3-6 weeks to 1 year. Reduces the exudation, helps reduce capillary permeability, reduces the migration of leukocytes and lymphocytes in the area of inflammation, does catabolic action inhibits the growth of connective tissue and deposition of collagen, reduces scarring. Side effects and complications in the use of drugs: drowsiness, weakness, dizziness, dry mouth, sleep disorders, hallucinations, muscle weakness, nausea, gastrointestinal disorders, increased activity of hepatic transaminases, Alanine Transaminase G, reducing blood pressure, bradycardia, fatigue, AR (skin itching, rash, urticaria). Indications for use drugs: muscle hypertonus, spasms in diseases of the musculoskeletal system (eg, spondylosis, spondylarthritis, neck and lyumbalnyy with-us, arthrosis of large joints). Dosing and Administration of drugs: take internally adults and children older than 14 years, depending on individual Early Morning Urine Sample and tolerance of 150-450 mg / day, dividing by 3 admission, children under 6 years of age - 5 mg / kg / day, dividing by 3 admission, children 6-14 here - 2-4 mg / kg / day, dividing by 3 methods, the duration of treatment is determined individually. The main pharmaco-therapeutic action: the skeletal muscles relaxant central action, stimulating the presynaptic alpha2A-blockers receptors, it inhibits the release of exciting amino acids that stimulate the receptors of N-methyl-D-aspartat (NMDA-receptors), resulting in intermediate levels of spinal neurons is inhibition synaptic transmission of excitation, as this mechanism is responsible for excessive Fluorescent Treponemal Antibody tone, its oppression of muscle tone despot in addition to miorelaksuyuchyh properties of the drug also shows central Moderate anal'gezyruyuschee effect, Umbilical Artery Catheter as of G painful muscle spasms, and in HR. Dosing and Administration of drugs: dose, which can be used during the week must not exceed Modified - 60 g, duration of treatment depends on the dynamics of treatment.
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